Web App That Request Data from Another Web Site every 12-hours

[nilamo]

That depends on what the data is. It might make more sense to just store it in a plain text file, and read it once when the server starts up. It's really hard to say what you "should" do, because we really don't have any idea what you're doing, what sort of traffic you're expecting, what the data is, etc.

I mean, you could just do it, and see if you're happy with the performance you're getting.